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CEACAM6 antibody (Middle Region)

CEACAM6 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776853
  • Target See all CEACAM6 Antibodies
    CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 43
    • 2
    • 2
    • 1
    Human
    Host
    • 35
    • 8
    Rabbit
    Clonality
    • 34
    • 9
    Polyclonal
    Conjugate
    • 18
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CEACAM6 antibody is un-conjugated
    Application
    • 24
    • 21
    • 10
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    EIQNPASANR SDPVTLNVLY GPDGPTISPS KANYRPGENL NLSCHAASNP
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against CEACAM6. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CEACAM6
    Top Product
    Discover our top product CEACAM6 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 344 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kobayashi, Miki, Ebina, Abe, Mori, Narumi, Suzuki, Sato, Maemondo, Endo, Inoue, Kumamoto, Kondo, Yamada-Okabe, Nukiwa, Sasano: "Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma." in: British journal of cancer, Vol. 107, Issue 10, pp. 1745-53, (2012) (PubMed).

  • Target
    CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))
    Alternative Name
    CEACAM6 (CEACAM6 Products)
    Synonyms
    CD66c antibody, CEAL antibody, NCA antibody, carcinoembryonic antigen-related cell adhesion molecule 6 antibody, carcinoembryonic antigen related cell adhesion molecule 6 antibody, Ceacam6 antibody, CEACAM6 antibody
    Background
    Many breast, pancreatic, colonic and non-small-cell lung carcinoma lines express CEACAM6 and CEACAM5, and antibodies to both can affect tumor cell growth in vitro and in vivo. CEACAM6 expression is elevated in many solid tumors, but variable as a function of histotype. It may be a promising target for antibody-based therapy.
    Alias Symbols: CD66c, CEAL, NCA
    Protein Interaction Partner: CARTPT, CEACAM6, CEACAM8, CEACAM7, CEACAM5, CEACAM1, APP,
    Protein Size: 344
    Molecular Weight
    38 kDa
    Gene ID
    4680
    NCBI Accession
    NM_002483, NP_002474
    UniProt
    P40199
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