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SLC22A1 antibody (C-Term)

SLC22A1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776916
  • Target See all SLC22A1 Antibodies
    SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
    Binding Specificity
    • 13
    • 8
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 48
    • 9
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 40
    • 9
    • 1
    Rabbit
    Clonality
    • 41
    • 9
    Polyclonal
    Conjugate
    • 23
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SLC22A1 antibody is un-conjugated
    Application
    • 32
    • 24
    • 17
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    IAIQMICLVN AELYPTFVSG VGPACRGSDA TSSRDQGGRF ARDHEGRREP
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SLC22A1. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human SLC22A1
    Top Product
    Discover our top product SLC22A1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 506 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Salomon, Muchitsch, Gausterer, Schwagerus, Huwer, Daum, Lehr, Ehrhardt: "The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier." in: Molecular pharmaceutics, Vol. 11, Issue 3, pp. 995-1006, (2014) (PubMed).

  • Target
    SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
    Alternative Name
    SLC22A1 (SLC22A1 Products)
    Synonyms
    SLC22A1 antibody, OCT1 antibody, HOCT1 antibody, oct1_cds antibody, Lx1 antibody, Oct1 antibody, Orct antibody, Orct1 antibody, Roct1 antibody, SLC22A2 antibody, solute carrier family 22 member 1 antibody, solute carrier family 22 (organic cation transporter), member 1 antibody, solute carrier family 22 member 2-like antibody, SLC22A1 antibody, Slc22a1 antibody, LOC421584 antibody
    Background
    Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The protein contains twelve putative transmembrane domains and is a plasma integral membrane protein.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
    Alias Symbols: HOCT1, OCT1, oct1_cds
    Protein Interaction Partner: CERS2, POU2AF1,
    Protein Size: 506
    Molecular Weight
    56 kDa
    Gene ID
    6580
    NCBI Accession
    NM_153187, NP_694857
    UniProt
    O15245
    Pathways
    Hormone Transport
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