F12 antibody (N-Term)
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- Target See all F12 Antibodies
- F12 (Coagulation Factor XII (F12))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This F12 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MRALLLLGFL LVSLESTLSI PPWEAPKEHK YKAEEHTVVL TVTGEPCHFP
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against F12. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human F12
- Top Product
- Discover our top product F12 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 615 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- F12 (Coagulation Factor XII (F12))
- Alternative Name
- F12 (F12 Products)
- Synonyms
- HAE3 antibody, HAEX antibody, HAF antibody, FXII antibody, coagulation factor XII antibody, coagulation factor XII (Hageman factor) antibody, F12 antibody
- Background
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This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type
Alias Symbols: HAE3, HAEX, HAF
Protein Interaction Partner: UBE2D3, UBE2D2, UBE2D1, UBC, HIF1A, UBE2N, UBE2E1, EPAS1, MMP12, MMP14, MMP13, GP1BA, KLKB1, KRT1, APOH, CD93, APP,
Protein Size: 615 - Molecular Weight
- 26 kDa
- Gene ID
- 2161
- NCBI Accession
- NM_000505, NP_000496
- UniProt
- P00748
- Pathways
- Complement System
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