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PLAP antibody (C-Term)

ALPP Reactivity: Human, Mouse, Rat, Dog, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777088
  • Target See all PLAP (ALPP) Antibodies
    PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))
    Binding Specificity
    • 21
    • 19
    • 16
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Dog, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse
    Host
    • 74
    • 54
    • 2
    Rabbit
    Clonality
    • 67
    • 62
    Polyclonal
    Conjugate
    • 70
    • 11
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLAP antibody is un-conjugated
    Application
    • 93
    • 53
    • 53
    • 36
    • 23
    • 19
    • 15
    • 13
    • 12
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    TVLLYGNGPG YVLKDGARPD VTESESGSPE YRQQSAVPLD EETHAGEDVA
    Predicted Reactivity
    Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 79%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against ALPP. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human ALPP
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    Discover our top product ALPP Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 535 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • Target
    PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))
    Alternative Name
    ALPP (ALPP Products)
    Synonyms
    ECK0378 antibody, JW0374 antibody, psiA antibody, ALP antibody, PALP antibody, PLAP antibody, PLAP-1 antibody, ILC antibody, CTACK antibody, ESkine antibody, Akp2 antibody, alp antibody, zgc:56672 antibody, DDBDRAFT_0205491 antibody, DDBDRAFT_0231570 antibody, DDB_0205491 antibody, DDB_0231570 antibody, ALPI antibody, Actn2lp antibody, Alp antibody, bacterial alkaline phosphatase antibody, alkaline phosphatase, placental antibody, alkaline phosphatase, placental type antibody, C-C motif chemokine ligand 27 antibody, alkaline phosphatase, liver/bone/kidney antibody, alkaline phosphatase antibody, alkaline phosphatase, intestinal antibody, PDZ and LIM domain 3 antibody, phoA antibody, ALPP antibody, LOC100436725 antibody, CCL27 antibody, alpl antibody, alp antibody, ALPI antibody, Pdlim3 antibody, Alpp antibody
    Background
    There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. ALPP is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form.There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
    Alias Symbols: ALP, PLAP, PALP
    Protein Interaction Partner: COL2A1, KRTAP10-3, KRTAP4-12, KRTAP5-9, RPA3, RPA2, RPA1, FBXO6, LATS1, UBC, SUMO1, SUMO2, UBXN6, Cep76, Trim69, Erh, Cbx1, UBXN11, ASPSCR1, NSFL1C, UBXN1, UBXN7, FAF2, FAF1, ALPP, PIGK, GPLD1,
    Protein Size: 535
    Molecular Weight
    59 kDa
    Gene ID
    250
    NCBI Accession
    NM_001632, NP_001623
    UniProt
    P05187
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