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LEFTY2 antibody (N-Term)

LEFTY2 Reactivity: Human, Mouse, Rat, Pig, Cow, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777146
  • Target See all LEFTY2 Antibodies
    LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))
    Binding Specificity
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Pig, Cow, Horse
    Host
    • 32
    • 6
    • 2
    • 1
    Rabbit
    Clonality
    • 35
    • 6
    Polyclonal
    Conjugate
    • 26
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LEFTY2 antibody is un-conjugated
    Application
    • 33
    • 15
    • 13
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    MWPLWLCWAL WVLPLAGPGA ALTEEQLLGS LLRQLQLSEV PVLDRADMEK
    Predicted Reactivity
    Cow: 79%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 83%
    Characteristics
    This is a rabbit polyclonal antibody against LEFTY2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human LEFTY2
    Top Product
    Discover our top product LEFTY2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 366 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))
    Alternative Name
    LEFTY2 (LEFTY2 Products)
    Synonyms
    EBAF antibody, LEFTA antibody, LEFTYA antibody, TGFB4 antibody, AI450052 antibody, Ebaf antibody, Leftb antibody, Stra3 antibody, Tgfb4 antibody, lefty antibody, lefty-1 antibody, atv2 antibody, cb720 antibody, fe38b03 antibody, wu:fe38b03 antibody, 6030463A22Rik antibody, AV214969 antibody, Lefta antibody, Ebaf2 antibody, left-right determination factor 2 antibody, left right determination factor 1 antibody, lefty2 antibody, Left-right determination factor 2 antibody, left-right determination factor 2-like antibody, LEFTY2 antibody, Lefty1 antibody, lft2 antibody, Lefty2 antibody, LOC699676 antibody, LOC100232580 antibody
    Background
    LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in its gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of its gene in the endometrium.This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.
    Alias Symbols: EBAF, LEFTA, LEFTYA, MGC46222, TGFB4
    Protein Interaction Partner: ACSS3,
    Protein Size: 366
    Molecular Weight
    40 kDa
    Gene ID
    7044
    NCBI Accession
    NM_003240, NP_003231
    UniProt
    O00292
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