PBX1 antibody (N-Term)

Catalog No. ABIN2777186

Product Details anti-PBX1 Antibody

Target: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBX1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDEQPRLMHS HAGVGMAGHP GLSQHLQDGA GGTEGEGGRK QDIGDILQQI

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PBX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PBX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 430 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PBX1

Target: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Alternative Name: PBX1 (PBX1 Products)

Synonyms: fi29e01 antibody, pbx1b antibody, wu:fi29e01 antibody, zgc:55265 antibody, 2310056B04Rik antibody, AI848790 antibody, AU015730 antibody, D230003C07Rik antibody, Pbx-1 antibody, Pbx1a antibody, Pbx1b antibody, PBX1A antibody, Xpbx1 antibody, Xpbx1b antibody, PBX homeobox 1 antibody, pre-B-cell leukemia homeobox 1a antibody, pre B cell leukemia homeobox 1 antibody, pre-B-cell leukemia homeobox 1 S homeolog antibody, PBX1 antibody, pbx1a antibody, Pbx1 antibody, pbx1.S antibody

Background: PBX1 binds the sequence 5'-ATCAATCAA-3'. It acts as a transcriptional activator of PF4 in complex with MEIS1. It may be converted into a potent transcriptional activator by the (1,19) translocation. It also may have a role in steroidogenesis and, subsequently, sexual development and differentiation.
Alias Symbols: DKFZp686B09108, MGC126627
Protein Interaction Partner: SMARCD3, HOXA1, UCHL3, MDM2, UBC, KAT2A, HOXC8, NEDD4L, ELAVL1, MEIS2, PDX1, CREBBP, MEIS1, SIN3B, HDAC3, POU2F1, HDAC1, SMARCA4, HOXA10, MYOD1, PBX2, PAX6, PKNOX1, MYH10, HOXD10, HOXD4, HOXB1, HOXB8, HOXA9, HOXA5, NR3C1, HOXD9, HOXB7,
Protein Size: 430

Molecular Weight: 47 kDa

Gene ID: 5087

NCBI Accession: NM_002585, NP_002576

UniProt: P40424