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NFIL3 antibody (Middle Region)

NFIL3 Reactivity: Human, Mouse, Rat, Cow, Sheep, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777219
  • Target See all NFIL3 Antibodies
    NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
    Binding Specificity
    • 11
    • 9
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 42
    • 17
    • 16
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Sheep, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Rabbit
    Host
    • 40
    • 1
    • 1
    Rabbit
    Clonality
    • 42
    Polyclonal
    Conjugate
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NFIL3 antibody is un-conjugated
    Application
    • 35
    • 20
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    GYSHSPPLLQ VNRSSSNSPR TSETDDGVVG KSSDGEDEQQ VPKGPIHSPV
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against NFIL3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human NFIL3
    Top Product
    Discover our top product NFIL3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 462 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
    Alternative Name
    NFIL3 (NFIL3 Products)
    Synonyms
    e4bp4 antibody, il3bp1 antibody, nfil3a antibody, nf-il3a antibody, MGC107826 antibody, NFIL3 antibody, E4BP4 antibody, IL3BP1 antibody, NF-IL3A antibody, NFIL3A antibody, E4BP4-1 antibody, zgc:100867 antibody, AV225605 antibody, nuclear factor, interleukin 3 regulated antibody, nuclear factor, interleukin 3 regulated L homeolog antibody, nuclear factor, interleukin 3, regulated antibody, nfil3 antibody, NFIL3 antibody, Nfil3 antibody, nfil3.L antibody
    Background
    NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
    Alias Symbols: E4BP4, IL3BP1, NF-IL3A, NFIL3A
    Protein Interaction Partner: AMOTL2, TRAF2, MAFF, BATF, NFIL3, MAFG, DDIT3, CBX8, SUMO2, UBC, CREB3, DR1,
    Protein Size: 462
    Molecular Weight
    51 kDa
    Gene ID
    4783
    NCBI Accession
    NM_005384, NP_005375
    UniProt
    Q16649
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