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IRF8 antibody (C-Term)

IRF8 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777225
  • Target See all IRF8 Antibodies
    IRF8 (Interferon Regulatory Factor 8 (IRF8))
    Binding Specificity
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 31
    • 24
    • 10
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig
    Host
    • 43
    • 2
    • 1
    Rabbit
    Clonality
    • 45
    • 1
    Polyclonal
    Conjugate
    • 32
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRF8 antibody is un-conjugated
    Application
    • 26
    • 17
    • 10
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    QLAEEAGKSC GAGSVMQAPE EPPPDQVFRM FPDICASHQR SFFRENQQIT
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against IRF8. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product IRF8 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 426 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ye, Wang, Wang, Wang, Song, Hou, Zhou, Li, Ho: "CD56+ T cells inhibit hepatitis C virus replication in human hepatocytes." in: Hepatology (Baltimore, Md.), Vol. 49, Issue 3, pp. 753-62, (2009) (PubMed).

  • Target
    IRF8 (Interferon Regulatory Factor 8 (IRF8))
    Alternative Name
    IRF8 (IRF8 Products)
    Synonyms
    zgc:92252 antibody, IRF8 antibody, MGC140338 antibody, DKFZp469B0320 antibody, H-ICSBP antibody, ICSBP antibody, ICSBP1 antibody, IRF-8 antibody, icsbp1 antibody, AI893568 antibody, Icsbp1 antibody, Myls antibody, interferon regulatory factor 8 antibody, interferon regulatory factor 8 L homeolog antibody, irf8 antibody, IRF8 antibody, irf8.L antibody, Irf8 antibody
    Background
    Interferon regulatory factor 8 (IRF8, interferon consensus sequence-binding protein, ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-. and IFN-.. IRF family proteins also control expression of IFN-. and IFN-.-regulated genes that are induced by viral infection.
    Alias Symbols: H-ICSBP, ICSBP, ICSBP1, IRF-8
    Protein Interaction Partner: SPI1, IRF1, TOP1, ZBTB17, PDGFRB, CBL, UBC, COPS4, COPS5, COPS6, COPS2, MID1, IRF6, GPS1, CDK4, SQSTM1, TRAF6, SMURF2, IRF2, TRIM21, IRF8, ETV6, RELA, NFKB1,
    Protein Size: 426
    Molecular Weight
    48 kDa
    Gene ID
    3394
    NCBI Accession
    NM_002163, NP_002154
    UniProt
    Q02556
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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