NFE2 antibody (C-Term)

Catalog No. ABIN2777229

Product Details anti-NFE2 Antibody

Target: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Horse, Cow, Guinea Pig, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFE2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ARGEADRTLE VMRQQLAELY HDIFQHLRDE SGNSYSPEEY VLQQAADGAI

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Nfe2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Nfe2

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NFE2

Target: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Alternative Name: Nfe2 (NFE2 Products)

Synonyms: NF-E2 antibody, p45 antibody, 45kDa antibody, p45NFE2 antibody, p45nf-e2 antibody, nuclear factor, erythroid 2 antibody, nuclear factor, erythroid derived 2 antibody, NFE2 antibody, Nfe2 antibody

Background: Nfe2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation.It binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. It requires MAFK or other small MAF proteins for binding to the NF-E2 motif. It may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Alias Symbols: 45 kDa, NF-E2, p45, p45NFE2, p45nf-e2
Protein Interaction Partner: Psmd4, Kmt2d, Rbbp5, Wdr5, Ash2l, Men1, Mafk, H3f3a, Crebbp, Mapk8, Trip4, Plrg1, Pdlim4, Zfp292, Gtf2h2, Zscan2, Ubp1, Tsg101, Tial1, Supt4a, Snai1, Kdm5d, Kdm5c, Dpf2, Per1, Kat2b, Mybbp1a, Orc2, Ikbkg, Hoxb4, Hoxa4, Hcls1, Gtf2h1, Foxn2, E4f1, Dlx5, Ci
Protein Size: 373

Molecular Weight: 41 kDa

Gene ID: 18022

NCBI Accession: NM_008685, NP_032711

UniProt: Q07279