DR1 antibody (Middle Region)

Catalog No. ABIN2777245

Product Details anti-DR1 Antibody

Target: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Zebrafish (Danio rerio), Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KKTISPEHVI QALESLGFGS YISEVKEVLQ ECKTVALKRR KASSRLENLG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Dr1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 176 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DR1

Target: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Alternative Name: Dr1 (DR1 Products)

Synonyms: BG:DS00929.3 antibody, CG4185 antibody, Dmel\\CG4185 antibody, Dr1 antibody, NC2 beta antibody, Nc2b antibody, dDr1 antibody, dNC2 antibody, wu:fj15f04 antibody, zgc:152914 antibody, 1700121L09Rik antibody, Dr1l antibody, NC2 antibody, NC2beta antibody, NC2-BETA antibody, Negative Cofactor 2beta antibody, TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN antibody, TATA-binding protein-associated phosphoprotein antibody, putative tata-binding protein-associated phosphoprotein antibody, down-regulator of transcription 1 antibody, down-regulator of transcription 1, TBP-binding (negative cofactor 2) antibody, NC2beta antibody, ECU11_0730 antibody, EDI_229030 antibody, PTRG_08168 antibody, Smp_160150 antibody, EBI_26279 antibody, EBI_23074 antibody, VDBG_02216 antibody, dr1 antibody, Dr1 antibody, DR1 antibody

Background: The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Dr1 can bind to DNA on its own. It is a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Alias Symbols: 1700121L09Rik, Dr1l, NC2, NC2beta
Protein Interaction Partner: Csrp2bp,
Protein Size: 176

Molecular Weight: 19 kDa

Gene ID: 13486

NCBI Accession: NM_026106, NP_080382

UniProt: Q91WV0