GTF2H3 antibody (N-Term)

Catalog No. ABIN2777299

Product Details anti-GTF2H3 Antibody

Target: GTF2H3 (General Transcription Factor IIH, Polypeptide 3, 34kD (GTF2H3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2H3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: VIASHIQESR FLYPGKNGRL GDFFGDPGNP PEFNPSGSKD GKYELLTSAN

Predicted Reactivity: Cow: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GTranscription Factor Antibodies2H3. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2H3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 308 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GTF2H3

Target: GTF2H3 (General Transcription Factor IIH, Polypeptide 3, 34kD (GTF2H3))

Alternative Name: GTF2H3 (GTF2H3 Products)

Synonyms: DDBDRAFT_0167192 antibody, DDBDRAFT_0230196 antibody, DDB_0167192 antibody, DDB_0230196 antibody, btf2 antibody, tfb4 antibody, tfiih antibody, 34kDa antibody, 5033417D07Rik antibody, BTF2 antibody, BTF2 p34 antibody, C730029A10 antibody, D5Ertd679e antibody, TFIIH antibody, GB12027 antibody, fc26a07 antibody, zgc:92759 antibody, wu:fc26a07 antibody, P34 antibody, TFB4 antibody, general transcription factor IIH, polypeptide 3 antibody, general transcription factor IIH subunit 3 antibody, gtf2h3 antibody, GTF2H3 antibody, Gtf2h3 antibody, LOC411231 antibody

Background: GTranscription Factor Antibodies2H3 interacts with HIV-1 Tat as a component of the HIV-1 transcription pre-initiation complex, but is released from the elongation complex which includes P-TEFb. It synergizes with HIV-1 Tat to induce transcription elongation from the HIV-1 LTR promoter.
Alias Symbols: BTF2, TFB4, TFIIH
Protein Interaction Partner: GTF2H2C_2, UBC, RPA3, RPA2, RPA1, CDK7, HEATR5A, MNAT1, GTF2H4, GTF2H2, GTF2H1, ERCC3, XBP1P1, ERCC2, AR,
Protein Size: 308

Molecular Weight: 34 kDa

Gene ID: 2967

NCBI Accession: NM_001516, NP_001507

UniProt: Q13889

Pathways: DNA Damage Repair