HEYL antibody (N-Term)

Catalog No. ABIN2777466

Product Details anti-HEYL Antibody

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEYL antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MKRPKEPSGS DGESDGPIDV GQEGQLSQMA RPLSTPSSSQ MQARKKRRGI

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 85%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HEYL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HEYL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 328 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HEYL antibody (ABIN2777466)

Morrow, Cullen, Liu, Guha, Sweeney, Birney, Collins, Walls, Redmond, Cahill: "Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 29, Issue 7, pp. 1112-8, (2009) (PubMed).

Target Details for HEYL

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Alternative Name: HEYL (HEYL Products)

Synonyms: HESR3 antibody, HEY3 antibody, HRT3 antibody, bHLHb33 antibody, Hey3 antibody, Hrt3 antibody, hesr3 antibody, fk74e12 antibody, wu:fk74e12 antibody, hes related family bHLH transcription factor with YRPW motif-like antibody, hairy/enhancer-of-split related with YRPW motif-like antibody, hes-related family bHLH transcription factor with YRPW motif-like antibody, HEYL antibody, Heyl antibody, heyl antibody

Background: HEYL belongs to hairy-related bHLH transcription factor family. HEY genes are candidates for several human or mouse disease loci.
Alias Symbols: HEY3, HRT3, bHLHb33
Protein Interaction Partner: RPGRIP1, RBPMS, MDFI, ZNF512B, HIPK3, LAPTM5, SKIL, ATXN1, PPP1CA, SMAD9, SMAD7, SMAD3, HTT, APP, UBC, SP8, ATF7IP, HAND2, HAND1,
Protein Size: 328

Molecular Weight: 35 kDa

Gene ID: 26508

NCBI Accession: NM_014571, NP_055386

UniProt: Q9NQ87

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling