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GTF2I antibody (N-Term)

GTF2I Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777491
  • Target See all GTF2I Antibodies
    GTF2I (General Transcription Factor III (GTF2I))
    Binding Specificity
    • 13
    • 8
    • 8
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 63
    • 23
    • 17
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit
    Host
    • 59
    • 4
    Rabbit
    Clonality
    • 60
    • 3
    Polyclonal
    Conjugate
    • 36
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GTF2I antibody is un-conjugated
    Application
    • 50
    • 32
    • 15
    • 14
    • 10
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    ILSPGGSCGP IKVKTEPTED SGISLEMAAV TVKEESEDPD YYQYNIQGSH
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against GTF2I. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2I
    Top Product
    Discover our top product GTF2I Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 978 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    GTF2I (General Transcription Factor III (GTF2I))
    Alternative Name
    GTF2I (GTF2I Products)
    Synonyms
    BAP135 antibody, BTKAP1 antibody, DIWS antibody, GTFII-I antibody, IB291 antibody, SPIN antibody, TFII-I antibody, WBS antibody, WBSCR6 antibody, Gtf2ird1 antibody, 6030441I21Rik antibody, BAP-135 antibody, GtfII-I antibody, Spin antibody, bap-135 antibody, bap135 antibody, btkap1 antibody, diws antibody, gtfii-i antibody, ib291 antibody, spin antibody, tfii-i antibody, wbs antibody, wbscr6 antibody, gtf2i antibody, gtf2i.L antibody, general transcription factor IIi antibody, general transcription factor II I antibody, general transcription factor IIi S homeolog antibody, GTF2I antibody, Gtf2i antibody, gtf2i antibody, gtf2i.S antibody
    Background
    GTF2I encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants.
    Alias Symbols: WBS, DIWS, SPIN, IB291, BAP135, BTKAP1, TFII-I, WBSCR6, GTFII-I
    Protein Interaction Partner: TP53, ZMYM3, PIAS2, TUBG1, TRAF6, SUMO2, SUMO3, AP2B1, DPY30, GCC1, MTUS2, MDM2, UBC, SUMO1, RPA3, RPA2, RPA1, EED, RNF2, SUZ12, CTPS2, WARS, RPL28, RAD23B, PRPS2, PRKDC, NUCB1, METTL1, ADSL, FBXO6, UBD, CBX2, TAB2, AP4S1, CBX4, MAPK12, C4BPA, MAP3K3, SLU
    Protein Size: 978
    Molecular Weight
    110 kDa
    Gene ID
    2969
    NCBI Accession
    NM_033000, NP_127493
    UniProt
    Q75M86
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