PAX6 antibody (N-Term)
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- Target See all PAX6 Antibodies
- PAX6 (Paired Box 6 (PAX6))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Cow, Horse, Dog, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PAX6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GRPLPDSTRQ KIVELAHSGA RPCDISRILQ THADAKVQVL DNQNVSNGCV
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PAX6. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PAX6
- Top Product
- Discover our top product PAX6 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 436 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PAX6 (Paired Box 6 (PAX6))
- Alternative Name
- PAX6 (PAX6 Products)
- Synonyms
- pax6 antibody, an2 antibody, mgda antibody, wagr antibody, pax-6 antibody, pax6a antibody, xpax6 antibody, XLPAX6 antibody, MGC52531 antibody, PAX-6 antibody, AN antibody, AN2 antibody, D11S812E antibody, MGDA antibody, WAGR antibody, Pax-6 antibody, pax6b antibody, 1500038E17Rik antibody, AEY11 antibody, Dey antibody, Gsfaey11 antibody, Sey antibody, PAXZF-A antibody, Pax6.1 antibody, cb280 antibody, fc20e07 antibody, pax-a antibody, pax[zf-a] antibody, paxzfa antibody, wu:fc20e07 antibody, zfpax-6a antibody, zfpax-6b antibody, paired box 6 antibody, paired box 6 L homeolog antibody, paired box 6 S homeolog antibody, paired box 6a antibody, PAX6 antibody, pax6 antibody, Pax6 antibody, pax6.L antibody, pax6.S antibody, pax6a antibody
- Background
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PAX6 is one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA,This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause aniridia as well as Peter's anomaly, both ocular diseases.
Alias Symbols: AN, AN2, D11S812E, MGC17209, MGDA, WAGR
Protein Interaction Partner: IPO13, Dlg4, NKIRAS2, Cacnb3, Pax6, Diap1, SMAD5, SMAD4, SMAD3, SMAD1, AR, HIPK2, SUMO1, SMARCA4, TP73, SHANK3, PBX1, VSX2, EN1, TRIM11, HOMER3, SIX3, INADL, EP300, SOX10, RGS3, DIAPH1, MAFG, RAX, DYNLL1, DLG1, CDX2, TBP, SOX3, MITF, HOXB1, SOX2, LHX2, TA
Protein Size: 436 - Molecular Weight
- 48 kDa
- Gene ID
- 5080
- NCBI Accession
- NM_001604, NP_001595
- Pathways
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
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