KLF2 antibody (Kruppel-Like Factor 2 (Lung)) (Middle Region)

Details for Product anti-KLF2 Antibody No. ABIN2777573, Supplier: Log in to see
Antigen
  • lklf
  • MGC52512
  • klf2
  • LKLF
  • Lklf
  • Kruppel-like factor 2 (lung)
  • Krueppel-like factor 2
  • klf2
  • KLF2
  • Klf2
Epitope
Middle Region
25
15
12
11
8
4
4
2
2
2
2
2
2
1
1
1
Reactivity
Guinea Pig, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Zebrafish
108
44
29
17
10
4
3
3
3
2
2
2
1
1
1
1
1
Host
Rabbit
53
45
12
Clonality
Polyclonal
Conjugate
This KLF2 antibody is un-conjugated
4
4
4
4
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Application
Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (IHC), Western Blotting (WB)
74
37
18
13
10
5
5
2
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen The immunogen is a synthetic peptide directed towards the middle region of human KLF2
Blocking Peptide Blocking peptide for this product available: ABIN979016
Sequence PPAFGLFDDA AAAAAALGLA PPAARGLLTP PASPLELLEA KPKRGRRSWP
Predicted Reactivity Guinea Pig: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%, Zebrafish: 79%
Characteristics This is a rabbit polyclonal antibody against KLF2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name KLF2 (KLF2 Antibody Abstract)
Background KLF2 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. KLF2 binds to the CACCC box in the beta-globin gene promoter and activates transcription.
Alias Symbols: LKLF
Protein Interaction Partner: KAT2B, EP300, CREBBP, FBXW7, UBC, GSK3B, ELAVL1, SMURF1, WWP1, GATA5, GATA6, WEE1,
Protein Size: 355
Molecular Weight 37 kDa
Gene ID 10365
NCBI Accession NM_016270, NP_057354
UniProt Q9Y5W3
Research Area Chromatin and Nuclear Signaling, Transcription Factors, Angiogenesis
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 355 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-KLF2 antibody (Kruppel-Like Factor 2 (Lung)) (Middle Region) (ABIN2777573) WB Suggested Anti-KLF2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Immunohistochemistry (IHC) image for anti-KLF2 antibody (Kruppel-Like Factor 2 (Lung)) (Middle Region) (ABIN2777573) anti-Kruppel-Like Factor 2 (Lung) (KLF2) (Middle Region) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-KLF2 antibody (Kruppel-Like Factor 2 (Lung)) (Middle Region) (ABIN2777573) anti-Kruppel-Like Factor 2 (Lung) (KLF2) (Middle Region) antibody (Image 3)
Western Blotting (WB) image for anti-KLF2 antibody (Kruppel-Like Factor 2 (Lung)) (Middle Region) (ABIN2777573) Host: Rabbit
Target Name: KLF2
Sample Tissue: Hela Whole cell
La...
Product cited in: Yamada, Park, Mamonkin, Lacorazza: "Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Krüppel-like factors KLF4 and KLF2." in: Nature immunology, Vol. 10, Issue 6, pp. 618-26, 2009 (PubMed).

Background publications Saavedra, Patterson, West, Randell, Riches, Malcolm, Cool, Nick, Dinarello: "Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways." in: American journal of respiratory cell and molecular biology, Vol. 38, Issue 6, pp. 679-88, 2008 (PubMed).