Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1) (C-Term) antibody

Details for Product No. ABIN2777590, Supplier: Log in to see
Antigen
  • zgc:110081
  • ACS1
  • FACL1
  • FACL2
  • LACS
  • LACS1
  • LACS2
  • Acas
  • Acas1
  • Acs
  • FACS
  • Facl2
  • ACS
  • COAA
  • CER8
  • ECERIFERUM 8
  • LONG-CHAIN ACYL-COA SYNTHASE 1
  • T8I13.8
  • F13F21.14
  • F13F21_14
  • LATERAL ROOT DEVELOPMENT 2
  • LRD2
  • long-chain acyl-CoA synthetase 2
  • acyl-CoA synthetase long-chain family member 1
  • long-chain-fatty-acid-CoA ligase 1
  • long chain acyl-CoA synthetase 1
  • long-chain acyl-CoA synthetase 2
  • acsl1
  • ACSL1
  • PGTG_13183
  • Acsl1
  • LACS1
  • LACS2
Alternatives
anti-Cow (Bovine) Acyl-CoA Synthetase Long-Chain Family Member 1 antibody for Immunohistochemistry
Epitope
C-Term
21
18
15
11
3
3
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rat (Rattus), Zebrafish
66
33
33
12
4
3
3
3
3
2
2
1
Host
Rabbit
62
4
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
63
25
15
13
10
8
1
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human ACSL1
Blocking Peptide Blocking peptide for this product available: ABIN972846
Sequence GSFEELCRNK DVKKAILEDM VRLGKDSGLK PFEQVKGITL HPELFSIDNG
Predicted Reactivity Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%
Characteristics This is a rabbit polyclonal antibody against ACSL1. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name ACSL1 (Acsl1 Antibody Abstract)
Background ACSL1 encodes an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ACS1, FACL1, FACL2, LACS, LACS1, LACS2
Protein Interaction Partner: SUMO2, PARK2, ATP4A, UBC, NR3C2, ECT2, UBD,
Protein Size: 698
Molecular Weight 78 kDa
Gene ID 2180
NCBI Accession NM_001995, NP_001986
UniProt P33121
Research Area Cancer, Fatty Acids, Metabolism
Pathways Regulation of Lipid Metabolism by PPARalpha
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 698 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1) (C-Term) antibody (ABIN2777590) Human Hela
Product cited in: Golej, Askari, Kramer, Barnhart, Vivekanandan-Giri, Pennathur, Bornfeldt: "Long-chain acyl-CoA synthetase 4 modulates prostaglandin E? release from human arterial smooth muscle cells." in: Journal of lipid research, Vol. 52, Issue 4, pp. 782-93, 2011 (PubMed).

Background publications Ghosh, Barbosa, Singh: "Molecular cloning and sequencing of human palmitoyl-CoA ligase and its tissue specific expression." in: Molecular and cellular biochemistry, Vol. 151, Issue 1, pp. 77-81, 1996 (PubMed).

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