FOXN3 antibody (Middle Region)

Catalog No. ABIN2777624

Product Details anti-FOXN3 Antibody

Target: FOXN3 (Forkhead Box N3 (FOXN3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Guinea Pig, Horse, Rat, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXN3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HKKRQHFAKA RKVPSDTLPL KKRRTEKPPE SDDEEMKEAA GSLLHLAGIR

Predicted Reactivity: Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FOXN3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXN3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 468 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FOXN3

Target: FOXN3 (Forkhead Box N3 (FOXN3))

Alternative Name: FOXN3 (FOXN3 Products)

Synonyms: C14orf116 antibody, CHES1 antibody, PRO1635 antibody, 5430426H20Rik antibody, AA589593 antibody, AW556347 antibody, Ches1 antibody, Ches1l antibody, HTLFL1 antibody, FOXN3 antibody, ches1 antibody, pro1635 antibody, zgc:136571 antibody, foxn3b antibody, foxn3 antibody, foxn3a antibody, forkhead box N3 antibody, forkhead box N3 L homeolog antibody, forkhead box N3 S homeolog antibody, FOXN3 antibody, Foxn3 antibody, foxn3 antibody, foxn3.L antibody, foxn3.S antibody

Background: FOXN3 gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms.This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms.
Alias Symbols: C14orf116, CHES1, PRO1635
Protein Interaction Partner: EXOSC8, SRPK2, ELAVL1, MEN1,
Protein Size: 468

Molecular Weight: 51 kDa

Gene ID: 1112

NCBI Accession: NM_005197, NP_005188

UniProt: O00409