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REXO4 antibody (Middle Region)

REXO4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777670
  • Target See all REXO4 Antibodies
    REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))
    Binding Specificity
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 14
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 13
    • 1
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 10
    • 2
    • 1
    • 1
    This REXO4 antibody is un-conjugated
    Application
    • 9
    • 7
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PADIEAAIGP EAAKIARKQL GQSEGSVSLS LVKEQAFGGL TRALALDCEM
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against REXO4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human REXO4
    Top Product
    Discover our top product REXO4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 422 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

  • Target
    REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))
    Alternative Name
    REXO4 (REXO4 Products)
    Synonyms
    REXO4 antibody, REX4 antibody, XPMC2 antibody, XPMC2H antibody, Gm111 antibody, Xpmc2h antibody, xpmc2 antibody, im:7156740 antibody, si:ch73-209e20.4 antibody, REX4 homolog, 3'-5' exonuclease antibody, REX4, 3'-5' exonuclease antibody, RNA exonuclease 4 antibody, putative 3'-5' exonuclease antibody, REXO4 antibody, Rexo4 antibody, LOC100229203 antibody, rexo4.S antibody, CAALFM_C112440WA antibody, rexo4 antibody
    Background
    The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.
    Alias Symbols: XPMC2, XPMC2H, REX4
    Protein Interaction Partner: UBC, SIRT7, ESR2, ESR1,
    Protein Size: 422
    Molecular Weight
    47 kDa
    Gene ID
    57109
    NCBI Accession
    NM_020385, NP_065118
    UniProt
    Q9GZR2
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