LIM Domain Binding 2 Protein antibody (N-Term)

Catalog No. ABIN2777701

Product Details anti-LIM Domain Binding 2 Protein Antibody

Target: LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Guinea Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIM Domain Binding 2 Protein antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DDATLTLSFC LEDGPKRYTI GRTLIPRYFS TVFEGGVTDL YYILKHSKES

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against LDB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LDB2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 373 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LIM Domain Binding 2 Protein

Target: LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))

Alternative Name: LDB2 (LDB2 Products)

Synonyms: CLIM1 antibody, LDB1 antibody, AI035351 antibody, AW146358 antibody, CLP-36 antibody, Ldb3 antibody, CLIM-1 antibody, LDB2 antibody, ldb2 antibody, clim1 antibody, clim1b antibody, ldb2l antibody, ldb3 antibody, wu:fd16f11 antibody, zgc:92548 antibody, LIM domain binding 2 antibody, LIM domain binding 2a antibody, LIM domain binding 2 S homeolog antibody, LIM domain binding 2b antibody, LDB2 antibody, Ldb2 antibody, ldb2a antibody, ldb2.S antibody, ldb2b antibody

Background: LDB2 belongs to the LDB family. LDB2 binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. LIM domains are required for both inhibitory effects on LIM homeodomain transcription factors and synergistic transcriptional activation events. The inhibitory actions of the LIM domain can often be overcome by the LIM co-regulators known as CLIM2, LDB2 and NLI. LIM homeoproteins and CLIMs are involved in a variety of developmental processes.
Alias Symbols: LDB1, CLIM1
Protein Interaction Partner: LHX4, RILP, LMO3, RASIP1, SSBP3, SSBP2, LMO4, TSNAX, UBC, SSBP4, ISL1, LHX9, RLIM,
Protein Size: 373

Molecular Weight: 43 kDa

Gene ID: 9079

NCBI Accession: NM_001290, NP_001281

UniProt: O43679

Pathways: Stem Cell Maintenance