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Endoglin antibody (N-Term)

ENG Reactivity: Human, Mouse, Rat, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777735
  • Target See all Endoglin (ENG) Antibodies
    Endoglin (ENG)
    Binding Specificity
    • 16
    • 14
    • 12
    • 12
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 170
    • 61
    • 43
    • 17
    • 10
    • 3
    • 2
    Human, Mouse, Rat, Guinea Pig
    Host
    • 106
    • 86
    • 16
    • 1
    • 1
    Rabbit
    Clonality
    • 106
    • 103
    • 1
    Polyclonal
    Conjugate
    • 91
    • 27
    • 25
    • 25
    • 15
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Endoglin antibody is un-conjugated
    Application
    • 148
    • 125
    • 57
    • 57
    • 34
    • 19
    • 17
    • 15
    • 14
    • 13
    • 13
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    ILEVHVLFLE FPTGPSQLEL TLQASKQNGT WPREVLLVLS VNSSVFLHLQ
    Predicted Reactivity
    Guinea Pig: 91%, Human: 100%, Mouse: 91%, Rat: 91%
    Characteristics
    This is a rabbit polyclonal antibody against ENG. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ENG
    Top Product
    Discover our top product ENG Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 625 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Endoglin (ENG)
    Alternative Name
    ENG (ENG Products)
    Synonyms
    ENG antibody, MGC137842 antibody, DKFZp469D0419 antibody, END antibody, HHT1 antibody, ORW1 antibody, AI528660 antibody, AI662476 antibody, CD105 antibody, S-endoglin antibody, endoglin antibody, ENG antibody, Eng antibody
    Background
    Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.
    Alias Symbols: END, ORW, HHT1, ORW1, CD105
    Protein Interaction Partner: ENG, TGFBR2, TGFBR1, TGFB3, TGFB1, ACVRL1, TUFM, TCTEX1D4, TGFBR3, TGFB2, INHBA, BMP7, BMP2, ACVR2A, ACVR1, ACVR2B,
    Protein Size: 625
    Molecular Weight
    68 kDa
    Gene ID
    2022
    NCBI Accession
    NM_000118, NP_000109
    UniProt
    P17813
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