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RORC antibody (Middle Region)

RORC Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777822
  • Target See all RORC Antibodies
    RORC (RAR-Related Orphan Receptor C (RORC))
    Binding Specificity
    • 16
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 96
    • 53
    • 22
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Horse, Rabbit, Pig
    Host
    • 79
    • 17
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 82
    • 18
    Polyclonal
    Conjugate
    • 52
    • 7
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This RORC antibody is un-conjugated
    Application
    • 79
    • 37
    • 24
    • 24
    • 15
    • 13
    • 11
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    CHLEYSPERG KAEGRESFYS TGSQLTPDRC GLRFEEHRHP GLGELGQGPD
    Predicted Reactivity
    Cow: 92%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 79%, Rat: 86%
    Characteristics
    This is a rabbit polyclonal antibody against RORC. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RORC
    Top Product
    Discover our top product RORC Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 497 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Huang, Huang, Lee, Ng, Chang: "Postirradiation sinus mucosa disease in nasopharyngeal carcinoma patients." in: The Laryngoscope, Vol. 117, Issue 4, pp. 737-42, (2007) (PubMed).

  • Target
    RORC (RAR-Related Orphan Receptor C (RORC))
    Alternative Name
    RORC (RORC Products)
    Synonyms
    NR1F3 antibody, RORG antibody, RZR-GAMMA antibody, RZRG antibody, TOR antibody, Nr1f3 antibody, RORgamma antibody, Thor antibody, RAR related orphan receptor C antibody, RAR-related orphan receptor C antibody, RAR-related orphan receptor gamma antibody, RORC antibody, Rorc antibody
    Background
    RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: MGC129539, NR1F3, RORG, RZRG, TOR, RZR-GAMMA
    Protein Interaction Partner: EVI2A, NCOA6, EIF3I, CHD4, EIF4EBP1,
    Protein Size: 497
    Molecular Weight
    56 kDa
    Gene ID
    6097
    NCBI Accession
    NM_001001523, NP_001001523
    UniProt
    B3KUU9
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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