SOX11 antibody (Middle Region)

Catalog No. ABIN2777866

Product Details anti-SOX11 Antibody

Target: SOX11 (SRY (Sex Determining Region Y)-Box 11 (SOX11))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX11 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PHQQLLQPPG QQPSQLLRRY NVAKVPASPT LSSSAESPEG ASLYDEVRAG

Predicted Reactivity: Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against SOX11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SOX11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 441 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SOX11 antibody (ABIN2777866)

Shim, Kwan, Li, Lefebvre, Sestan: "Cis-regulatory control of corticospinal system development and evolution." in: Nature, Vol. 486, Issue 7401, pp. 74-9, (2012) (PubMed).

Target Details for SOX11

Target: SOX11 (SRY (Sex Determining Region Y)-Box 11 (SOX11))

Alternative Name: SOX11 (SOX11 Products)

Synonyms: XLS13 antibody, XLS13b antibody, xSOX-11 antibody, xls13a antibody, xsox11 antibody, SOX11 antibody, 1110038H03Rik antibody, 6230403H02Rik antibody, AI836553 antibody, end1 antibody, XLS13B antibody, sox11 antibody, sox11b antibody, sox13 antibody, xSox-13 antibody, sox11a antibody, cb237 antibody, id:ibd2104 antibody, wu:fb16g02 antibody, zgc:136533 antibody, SRY-box 11 antibody, SRY (sex determining region Y)-box 11 antibody, SRY-box 11 S homeolog antibody, SRY-box 11-like antibody, SRY box 11 antibody, SRY-box 11 L homeolog antibody, SRY (sex determining region Y)-box 11a antibody, SOX11 antibody, sox11 antibody, Sox11 antibody, sox11.S antibody, sox11.L antibody, sox11a antibody

Background: SOX11 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: POU3F3, POU3F2,
Protein Size: 441

Molecular Weight: 47 kDa

Gene ID: 6664

NCBI Accession: NM_003108, NP_003099

UniProt: P35716

Pathways: Tube Formation