TFAP2C antibody (Middle Region)

Catalog No. ABIN2777941

Product Details anti-TFAP2C Antibody

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFAP2C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SPPECLNASL LGGVLRRAKS KNGGRSLREK LDKIGLNLPA GRRKAAHVTL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TFAP2C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TFAP2C

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 450 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFAP2C

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Alternative Name: TFAP2C (TFAP2C Products)

Synonyms: erf1 antibody, hap-2g antibody, tfa2pc antibody, tfap2g antibody, ap2-gamma antibody, TFAP2C antibody, AP2-gamma antibody, Tcfap2c antibody, AP2-GAMMA antibody, ERF1 antibody, TFAP2G antibody, hAP-2g antibody, wu:fb48g05 antibody, wu:fb49c04 antibody, zgc:92088 antibody, ap-2g antibody, tfap2gamma antibody, AA409384 antibody, AP2gamma antibody, Ap-2.2 antibody, Stra2 antibody, transcription factor AP-2 gamma antibody, putative transcription factor ap-2 gamma antibody, transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) antibody, transcription factor AP-2 gamma S homeolog antibody, transcription factor AP-2, gamma antibody, tfap2c antibody, TFAP2C antibody, Smp_157840 antibody, Tfap2c antibody, tfap2c.S antibody

Background: TFAP2C is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AP2-GAMMA, ERF1, TFAP2G, hAP-2g
Protein Interaction Partner: ZFAND4, NR1I2, IKBKB, GPR22, CCNG1, KCTD1, SUMO1, UBE2I, BRCA1, HHV8GK18_gp81, KDM5B, MYC, ELAVL1, SUMO2, UBC, CITED4, CITED2, CITED1, TP53,
Protein Size: 450

Molecular Weight: 49 kDa

Gene ID: 7022

NCBI Accession: NM_003222, NP_003213

UniProt: Q92754

Pathways: Stem Cell Maintenance