Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

UBTF antibody (Middle Region)

UBTF Reactivity: Human, Mouse, Rat, Horse, Cow, Rabbit, Pig, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777960
  • Target See all UBTF Antibodies
    UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))
    Binding Specificity
    • 15
    • 11
    • 9
    • 8
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 66
    • 47
    • 32
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Horse, Cow, Rabbit, Pig, Guinea Pig
    Host
    • 65
    • 4
    Rabbit
    Clonality
    • 66
    • 3
    Polyclonal
    Conjugate
    • 29
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBTF antibody is un-conjugated
    Application
    • 50
    • 30
    • 13
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    LESLPEEEQQ RVLGEEKMLN INKKQATSPA SKKPAQEGGK GGSEKPKRPV
    Predicted Reactivity
    Cow: 86%, Guinea Pig: 79%, Horse: 77%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 93%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against UBTF. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human UBTF
    Top Product
    Discover our top product UBTF Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 764 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))
    Alternative Name
    UBTF (UBTF Products)
    Synonyms
    NOR-90 antibody, UBF antibody, UBF-1 antibody, UBF1 antibody, A930005G04Rik antibody, Tcfubf antibody, wu:fj38c10 antibody, si:dz180g5.3 antibody, ubf antibody, Ubtf antibody, ubf1 antibody, xUBF antibody, xUBFbeta2 antibody, UBTF antibody, nor-90 antibody, ubf2 antibody, ubtf antibody, upstream binding transcription factor, RNA polymerase I antibody, upstream binding transcription factor, RNA polymerase I L homeolog antibody, upstream binding transcription factor, RNA polymerase I S homeolog antibody, UBTF antibody, Ubtf antibody, ubtf antibody, ubtf.L antibody, ubtf.S antibody
    Background
    UBTF is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1. Two UBTF polypeptides, of 94 and 97 kD, exist in the human. UBTF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxesUpstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990 [PubMed 2330041]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: NOR-90, UBF, UBF1, UBF-1
    Protein Interaction Partner: UBC, MDM2, RNF2, Dlg4, ESR1, CDK4, CDK2, CCNE1, CCND1, WDR70, YEATS4, RB1, GRK5, KAT5, SIRT7, POLR1A, MYBBP1A, HDAC1, RUNX2, SUMO2, SMARCA5, MAPK3, MAPK1, SUMO1, PIK3CA, IRS1, TAF1D, tat, MCRS1, TLE1, ACTN4, POLR1E, CHGB, SMURF1, TCOF1, MAD1L1, ZMYM2, SER
    Protein Size: 764
    Molecular Weight
    89 kDa
    Gene ID
    7343
    NCBI Accession
    NM_014233, NP_055048
    UniProt
    P17480
Support