BHLHE41 antibody (Middle Region)

Catalog No. ABIN2778013

Product Details anti-BHLHE41 Antibody

Target: BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))

Binding Specificity: Middle Region

Reactivity: Human, Dog, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BHLHE41 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YCVPVIQRTQ PSAELAAEND TDTDSGYGGE AEARPDREKG KGAGASRVTI

Predicted Reactivity: Cow: 87%, Dog: 100%, Human: 100%, Pig: 100%

Characteristics: This is a rabbit polyclonal antibody against BHLHB3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BHLHB3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 482 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BHLHE41

Target: BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))

Alternative Name: BHLHB3 (BHLHE41 Products)

Synonyms: BHLHB3 antibody, dec2 antibody, bhlhb3 antibody, sharp1 antibody, sharp-1 antibody, MGC108143 antibody, DEC2 antibody, SHARP1 antibody, hDEC2 antibody, 6430520M22Rik antibody, Bhlhb2l antibody, Bhlhb3 antibody, Sharp1 antibody, Dec2 antibody, SHARP-1 antibody, basic helix-loop-helix family member e41 antibody, basic helix-loop-helix family, member e41 antibody, BHLHE41 antibody, bhlhe41 antibody, Bhlhe41 antibody

Background: BHLHB3 may be a transcriptional repressor that represses both basal and activated transcription. It play a role as a tumor suppressor for lung cancer. DEC1 and DEC2(BHLHB3) may play a crucial role in the adaptation to hypoxia and are regulators of the mammalian molecular clock, and form a fifth clock-gene family.
Alias Symbols: DEC2, SHARP-1, SHARP1, hDEC2, BHLHB3
Protein Interaction Partner: HDAC1, CEBPA, BHLHE41, PSMA4, HIF1A, BHLHE40, RXRA, SUMO2, SIRT1, MYOD1, CEBPB,
Protein Size: 482

Molecular Weight: 50 kDa

Gene ID: 79365

NCBI Accession: NM_030762, NP_110389

UniProt: Q9C0J9

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development