CBLL1 antibody (N-Term)

Catalog No. ABIN2778029

Product Details anti-CBLL1 Antibody

Target: CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBLL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDHTDNELQG TNSSGSLGGL DVRRRIPIKL ISKQANKAKP APRTQRTINR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CBLL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CBLL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 491 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CBLL1

Target: CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))

Alternative Name: CBLL1 (CBLL1 Products)

Synonyms: HAKAI antibody, RNF188 antibody, zgc:55308 antibody, CBLL1 antibody, AI467391 antibody, Hakai antibody, c-Cbl-like antibody, cbll1 antibody, hakai antibody, rnf188 antibody, Cbl proto-oncogene like 1 antibody, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase S homeolog antibody, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase antibody, Casitas B-lineage lymphoma-like 1 antibody, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase L homeolog antibody, CBLL1 antibody, cbll1.S antibody, Cbll1 antibody, cbll1 antibody, cbll1.L antibody

Background: Epithelial cell cadherin is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. CBLL1 is an E3 ubiquitin ligase that mediates ubiquitination of the CDH1 complex.Epithelial cell cadherin (CDH1, MIM 192090) is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. HAKAI is an E3 ubiquitin ligase (see UBE3A, MIM 601623) that mediates ubiquitination of the CDH1 complex.Epithelial cell cadherin (CDH1, MIM 192090) is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. HAKAI is an E3 ubiquitin ligase (see UBE3A, MIM 601623) that mediates ubiquitination of the CDH1 complex.[supplied by OMIM].
Alias Symbols: FLJ23109, HAKAI, MGC163401, MGC163403, RNF188
Protein Interaction Partner: DGCR6, SUMO1, UBC, CDH1, RNF2, YWHAQ, SFPQ, Cbll1, ESR1, CTTN, DOK1, SRC, CDC42,
Protein Size: 491

Molecular Weight: 55 kDa

Gene ID: 79872

NCBI Accession: NM_024814, NP_079090

UniProt: Q75N03