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Claudin 11 antibody (C-Term)

CLDN11 Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778048
  • Target See all Claudin 11 (CLDN11) Antibodies
    Claudin 11 (CLDN11)
    Binding Specificity
    • 15
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 23
    • 23
    • 21
    • 19
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse
    Host
    • 36
    Rabbit
    Clonality
    • 35
    • 1
    Polyclonal
    Conjugate
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Claudin 11 antibody is un-conjugated
    Application
    • 30
    • 14
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    VSFGYSLYAG WIGAVLCLVG GCVILCCAGD AQAFGENRFY YTAGSSSPTH
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%
    Characteristics
    This is a rabbit polyclonal antibody against CLDN11. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN11
    Top Product
    Discover our top product CLDN11 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 207 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Claudin 11 (CLDN11)
    Alternative Name
    CLDN11 (CLDN11 Products)
    Synonyms
    cldn11 antibody, fb97c11 antibody, wu:fb97c11 antibody, claudin-11 antibody, CLDN11 antibody, Claudin-11 antibody, DKFZp459H2322 antibody, OSP antibody, OTM antibody, Claudin11 antibody, Osp antibody, Otm antibody, claudin 11b antibody, claudin 11 antibody, cldn11b antibody, CLDN11 antibody, Cldn11 antibody
    Background
    CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.
    Alias Symbols: OSP, OTM
    Protein Interaction Partner: UBC, TSPAN3, TSPAN4,
    Protein Size: 207
    Molecular Weight
    22 kDa
    Gene ID
    5010
    NCBI Accession
    NM_005602, NP_005593
    UniProt
    O75508
    Pathways
    Hepatitis C
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