HAND1 antibody (N-Term)

Catalog No. ABIN2778103

Product Details anti-HAND1 Antibody

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Sheep, Cow, Guinea Pig, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAND1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CHQERPYFQS WLLSPADAAP DFPAGGPPPA AAAAATAYGP DARPGQSPGR

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against HAND1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HAND1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 215 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HAND1

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Alternative Name: HAND1 (HAND1 Products)

Synonyms: CATG antibody, CG antibody, Hxt antibody, Thing1 antibody, bHLHa27 antibody, eHand antibody, eHAND antibody, hand-1 antibody, hand1-A antibody, HXT antibody, HAND1 antibody, hxt antibody, thing1 antibody, EHAND antibody, Hand1 antibody, Ehand1 antibody, Th1 antibody, cathepsin G antibody, heart and neural crest derivatives expressed 1 antibody, heart and neural crest derivatives expressed 1 L homeolog antibody, CTSG antibody, HAND1 antibody, Hand1 antibody, hand1.L antibody, hand1 antibody

Background: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
Alias Symbols: Hxt, eHand, Thing1, bHLHa27, HAND1
Protein Interaction Partner: SRA1, HEYL, PPP2R5D, HEY2, FHL2, HAND2, HAND1, PRKACA, TCF12, PRKCA, MYOD1, TCF3, ACHE,
Protein Size: 215

Molecular Weight: 23 kDa

Gene ID: 9421

NCBI Accession: NM_004821, NP_004812

UniProt: O96004

Pathways: Tube Formation