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TNKS antibody (Middle Region)

TNKS Reactivity: Human, Mouse, Rat, Cow, Rabbit, Horse, Dog, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778109
  • Target See all TNKS Antibodies
    TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))
    Binding Specificity
    • 10
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 37
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Cow, Rabbit, Horse, Dog, Guinea Pig
    Host
    • 32
    • 3
    • 1
    • 1
    Rabbit
    Clonality
    • 34
    • 3
    Polyclonal
    Conjugate
    • 25
    • 4
    • 2
    • 2
    • 2
    • 2
    This TNKS antibody is un-conjugated
    Application
    • 31
    • 21
    • 17
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    VSASLISPAS TPSCLSAASS IDNLTGPLAE LAVGGASNAG DGAAGTERKE
    Predicted Reactivity
    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against TNKS. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TNKS
    Top Product
    Discover our top product TNKS Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1327 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))
    Alternative Name
    TNKS (TNKS Products)
    Synonyms
    wu:fe02c12 antibody, ARTD5 antibody, PARP-5a antibody, PARP5A antibody, PARPL antibody, TIN1 antibody, TINF1 antibody, TNKS1 antibody, pART5 antibody, 4930554K12Rik antibody, AI662855 antibody, C86528 antibody, D130072O21Rik antibody, TANK1 antibody, mTNKS1 antibody, tankyrase-1 antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b antibody, tankyrase antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 S homeolog antibody, tnksb antibody, TNKS antibody, Tnks antibody, tnks2.S antibody
    Background
    TNKS may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. It has PARP activity and can modify TERF1, and thereby contribute to the regulation of telomere length.
    Alias Symbols: PARP-5a, PARP5A, PARPL, TIN1, TINF1, TNKS1, pART5
    Protein Interaction Partner: RNF146, RAPGEF2, TINF2, TNKS, TERF1, SH3BP2, APC, BLZF1, GMDS, UBC, DISC1, TNIK, SH3BP5, TERF2, FANCD2, BABAM1, VPS33A, FNBP1, MCL1, POT1, TNKS2, TNKS1BP1, NUMA1, LNPEP,
    Protein Size: 1327
    Molecular Weight
    142 kDa
    Gene ID
    8658
    NCBI Accession
    NM_003747, NP_003738
    UniProt
    O95271
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