C4BPB antibody (Complement Component 4 Binding Protein, beta) (N-Term)

Details for Product anti-C4BPB Antibody No. ABIN2778139, Supplier: Log in to see
Antigen
  • C4BPB
  • C4BP
  • C4bp-ps1
  • complement component 4 binding protein, beta
  • C4BPB
  • C4bpb
Alternatives
anti-Human C4BPB antibody for Immunohistochemistry
Epitope
N-Term
9
7
7
6
5
3
3
2
1
Reactivity
Dog (Canine), Human, Pig (Porcine)
33
Host
Rabbit
27
6
Clonality
Polyclonal
Conjugate
This C4BPB antibody is un-conjugated
2
2
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
31
17
7
5
3
2
2
1
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human C4BPB
Blocking Peptide Blocking peptide for this product available: ABIN974251
Sequence CCLMVAWRVS ASDAEHCPEL PPVDNSIFVA KEVEGQILGT YVCIKGYHLV
Predicted Reactivity Dog: 86%, Human: 100%, Pig: 93%
Characteristics This is a rabbit polyclonal antibody against C4BPB. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name C4BPB (C4BPB Antibody Abstract)
Background C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C.
Alias Symbols: C4BP
Protein Interaction Partner: UBC, PROS1,
Protein Size: 252
Molecular Weight 28 kDa
Gene ID 725
NCBI Accession NM_000716, NP_000707
UniProt P20851
Pathways Complement System
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 252 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Immunohistochemistry (IHC) image for anti-Complement Component 4 Binding Protein, beta (C4BPB) (N-Term) antibody (ABIN2778139) anti-Complement Component 4 Binding Protein, beta (C4BPB) (N-Term) antibody
Western Blotting (WB) image for anti-Complement Component 4 Binding Protein, beta (C4BPB) (N-Term) antibody (ABIN2778139) WB Suggested Anti-C4BPB
Antibody Titration: 0.2-1 µg/mL
Positive Contro...
Product cited in: Emery, Erdman, Bowen, Newton, Winchell, Meyer, Tong, Cook, Holloway, McCaustland, Rota, Bankamp, Lowe, Ksiazek, Bellini, Anderson: "Real-time reverse transcription-polymerase chain reaction assay for SARS-associated coronavirus." in: Emerging infectious diseases, Vol. 10, Issue 2, pp. 311-6, 2004 (PubMed).

Background publications Anderson, Polanski, Pieper, Gatlin, Tirumalai, Conrads, Veenstra, Adkins, Pounds, Fagan, Lobley: "The human plasma proteome: a nonredundant list developed by combination of four separate sources." in: Molecular & cellular proteomics : MCP, Vol. 3, Issue 4, pp. 311-26, 2004 (PubMed).

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