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RGS17 antibody (C-Term)

RGS17 Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778238
  • Target See all RGS17 Antibodies
    RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
    Binding Specificity
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 14
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse, Dog
    Host
    • 10
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 13
    • 1
    Polyclonal
    Conjugate
    • 14
    This RGS17 antibody is un-conjugated
    Application
    • 13
    • 6
    • 4
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    NRNLLDPNPH MYEDAQLQIY TLMHRDSFPR FLNSQIYKSF VESTAGSSSE
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against RGS17. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human RGS17
    Top Product
    Discover our top product RGS17 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
    Alternative Name
    RGS17 (RGS17 Products)
    Synonyms
    RGS17 antibody, zgc:92802 antibody, MGC179306 antibody, RGS-17 antibody, RGSZ2 antibody, hRGS17 antibody, 6430507P11Rik antibody, Rgsz2 antibody, regulator of G protein signaling 17 antibody, regulator of G-protein signaling 17 antibody, RGS17 antibody, Rgs17 antibody, rgs17 antibody
    Background
    This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
    Alias Symbols: RGS-17, RGSZ2, hRGS17
    Protein Interaction Partner: LCE3C, LCE2A, LCE4A, TBC1D16, DHX37, NUFIP2, PTGER3, OTX1, RPL10A, SMCP, HOXA1, GNAI3, GNAI1, AQP1, ADRB2, RABEP1, RBBP8, UBC, OSTM1,
    Protein Size: 210
    Molecular Weight
    23 kDa
    Gene ID
    26575
    NCBI Accession
    NM_012419, NP_036551
    UniProt
    Q9UGC6
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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