TRIM13 antibody (Middle Region)

Catalog No. ABIN2778287

Product Details anti-TRIM13 Antibody

Target: TRIM13 (Tripartite Motif Containing 13 (TRIM13))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM13 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KVKEFFEKLQ HTLDQKKNEI LSDFETMKLA VMQAYDPEIN KLNTILQEQR

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RFP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RFP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 407 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM13

Target: TRIM13 (Tripartite Motif Containing 13 (TRIM13))

Alternative Name: RFP2 (TRIM13 Products)

Synonyms: TRIM13 antibody, RFP2 antibody, CAR antibody, DLEU5 antibody, LEU5 antibody, RNF77 antibody, 3110001L12Rik antibody, Rfp2 antibody, tripartite motif containing 13 antibody, ret finger protein 2 antibody, tripartite motif-containing 13 antibody, TRIM13 antibody, LOC100338599 antibody, Trim13 antibody

Background: The protein encoded by RFP2 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies near the nucleus, but its function is unknown. RFP2 is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia.
Alias Symbols: CAR, LEU5, RFP2, DLEU5, RNF77
Protein Interaction Partner: GMCL1, IKBKG, TRIM13, VCP, UBC, DDOST, CALM1, ATP2A2, UBE2D2, ZFYVE1, SQSTM1, ROBO2, CACNA1C, ARHGDIA, MDM2, AKT1,
Protein Size: 407

Molecular Weight: 45 kDa

Gene ID: 10206

NCBI Accession: NM_052811, NP_434698

UniProt: O60858