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ATF2 antibody (C-Term)

ATF2 Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778291
  • Target See all ATF2 Antibodies
    ATF2 (Activating Transcription Factor 2 (ATF2))
    Binding Specificity
    • 49
    • 36
    • 26
    • 26
    • 24
    • 24
    • 23
    • 23
    • 15
    • 15
    • 14
    • 14
    • 12
    • 10
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 294
    • 228
    • 205
    • 16
    • 12
    • 10
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Guinea Pig
    Host
    • 326
    • 12
    • 2
    • 1
    Rabbit
    Clonality
    • 312
    • 29
    Polyclonal
    Conjugate
    • 153
    • 20
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 8
    • 8
    • 5
    • 4
    This ATF2 antibody is un-conjugated
    Application
    • 240
    • 118
    • 112
    • 111
    • 75
    • 61
    • 59
    • 35
    • 33
    • 22
    • 15
    • 10
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    LRNEVAQLKQ LLLAHKDCPV TAMQKKSGYH TADKDDSSED ISVPSSPHTE
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against ATF2. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human ATF2
    Top Product
    Discover our top product ATF2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 505 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ATF2 (Activating Transcription Factor 2 (ATF2))
    Alternative Name
    ATF2 (ATF2 Products)
    Synonyms
    CRE-BP1 antibody, CREB2 antibody, HB16 antibody, TREB7 antibody, CG12850 antibody, CG3749 antibody, dATF-2 antibody, DmelCG30420 antibody, CG30420 antibody, CHN1 antibody, Atf-2 antibody, CRE-BP antibody, Creb2 antibody, D130078H02Rik antibody, D18875 antibody, Tg(Gzma-Klra1)7Wum antibody, mXBP antibody, atf2-A antibody, atf2l antibody, activating transcription factor 2 antibody, Activating transcription factor-2 antibody, activating transcription factor 2 S homeolog antibody, ATF2 antibody, Atf-2 antibody, Atf2 antibody, atf2.S antibody, atf2 antibody
    Background
    ATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.
    Alias Symbols: HB16, CREB2, TREB7, CRE-BP1
    Protein Interaction Partner: MAPK10, MAPK9, MAPK8, MAPK1, SUMO1, KIFC3, FOS, MAPK14, EXOSC8, JUN, CREBBP, ATF2, CEBPG, BACH1, ATF4, ATF3, BATF3, DDIT3, BATF, FOSL1, H2AFY, RB1, GAPDH, NME2P1, TUBB, SFXN1, RAB2B, TMX1, GRPEL1, COLGALT1, AHNAK, SQRDL, RTN4, APMAP, C19orf10, RAB14, ERO1
    Protein Size: 505
    Molecular Weight
    55 kDa
    Gene ID
    1386
    NCBI Accession
    NM_001880, NP_001871
    Pathways
    MAPK Signaling, RTK Signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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