SPIC antibody (Middle Region)

Catalog No. ABIN2778497

Product Details anti-SPIC Antibody

Target: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Binding Specificity: Middle Region

Reactivity: Human, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPIC antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LQRLSPSYFL GKEIFYSQCV QPDQEYLSLN NWNANYNYTY ANYHELNHHD

Predicted Reactivity: Cow: 86%, Horse: 79%, Human: 100%, Pig: 100%

Characteristics: This is a rabbit polyclonal antibody against SPIC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SPIC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 248 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPIC

Target: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Alternative Name: SPIC (SPIC Products)

Synonyms: SPI-C antibody, AU019198 antibody, C76795 antibody, Prf antibody, Spi-C antibody, zgc:101790 antibody, spi-c antibody, spic antibody, Spi-C transcription factor antibody, transcription factor Spi-C-like antibody, Spi-C transcription factor (Spi-1/PU.1 related) antibody, Spi-C transcription factor (Spi-1/PU.1 related) S homeolog antibody, SPIC antibody, LOC100349167 antibody, Spic antibody, spic antibody, spic.S antibody

Background: SPIC controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. SPIC is a transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. SPIC regulates VCAM1 gene expression.
Alias Symbols: MGC40611, SPI-C
Protein Interaction Partner: APP,
Protein Size: 248

Molecular Weight: 29 kDa

Gene ID: 121599

NCBI Accession: NM_152323, NP_689536

UniProt: Q8N5J4