HOXA9 antibody (Middle Region)

Catalog No. ABIN2778526

Product Details anti-HOXA9 Antibody

Target: HOXA9 (Homeobox A9 (HOXA9))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA9 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KEFLFNMYLT RDRRYEVARL LNLTERQVKI WFQNRRMKMK KINKDRAKDE

Predicted Reactivity: Cow: 85%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 85%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against HOXA9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXA9

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 272 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HOXA9 antibody (ABIN2778526)

Wang, Zeng, Chen, Ding, Zhong, Zhao, Wang, Sarver, Koller, Zhi, Ma, Yu, Chen, Huang: "BRCA1 is a negative modulator of the PRC2 complex." in: The EMBO journal, Vol. 32, Issue 11, pp. 1584-97, (2013) (PubMed).

Target Details for HOXA9

Target: HOXA9 (Homeobox A9 (HOXA9))

Alternative Name: HOXA9 (HOXA9 Products)

Synonyms: HOXA9 antibody, XlHbox-6 antibody, XlHbox6 antibody, hoxa9-A antibody, xhoxa9 antibody, HOXA-9 antibody, ABD-B antibody, HOX1 antibody, HOX1.7 antibody, HOX1G antibody, D6a9 antibody, Hox-1.7 antibody, Hox1r5 antibody, Hoxa7 antibody, homeobox A9 antibody, homeobox protein Hox-A9 antibody, homeobox A9 S homeolog antibody, homeobox A7 antibody, HOXA9 antibody, LOC745701 antibody, hoxa9 antibody, hoxa9.S antibody, Hoxa9 antibody, Hoxa7 antibody

Background: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA9 gene is part of the A cluster on chromosome 7 and the protein is a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ABD-B, HOX1, HOX1.7, HOX1G, MGC1934
Protein Interaction Partner: TRIP6, PRMT5, CUL4A, UBC, CREBBP, PBX3, RBPMS, PBX2, PBX1, PLSCR1, MEIS2, MEIS1, SMAD2, SMAD4, JUN, NFKBIA, BCR, KMT2A,
Protein Size: 272

Molecular Weight: 30 kDa

Gene ID: 3205

NCBI Accession: NM_152739, NP_689952

UniProt: P31269