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HIF3A antibody (C-Term)

HIF3A Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778530
  • Target See all HIF3A Antibodies
    HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
    Binding Specificity
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 28
    • 16
    • 13
    • 1
    Human
    Host
    • 26
    • 4
    • 1
    Rabbit
    Clonality
    • 30
    • 1
    Polyclonal
    Conjugate
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIF3A antibody is un-conjugated
    Application
    • 18
    • 11
    • 9
    • 5
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    PGSLQDPSTP LLNLNEPLGL GPSLLSPYSD EDTTQPGGPF QPRAGSAQAD
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against HIF3A. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human HIF3A
    Top Product
    Discover our top product HIF3A Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 667 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • Target
    HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
    Alternative Name
    HIF3A (HIF3A Products)
    Synonyms
    HIF-3A antibody, IPAS antibody, MOP7 antibody, PASD7 antibody, bHLHe17 antibody, Ipas antibody, NEPAS antibody, Mop7 antibody, HIF3A antibody, hypoxia inducible factor 3 alpha subunit antibody, hypoxia inducible factor 3, alpha subunit antibody, HIF3A antibody, Hif3a antibody
    Background
    HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression.The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene.
    Alias Symbols: IPAS, MOP7, PASD7, HIF-3A, bHLHe17
    Protein Interaction Partner: HSP90AA1, VHL, EGLN3, EGLN1, EGLN2, HIF1A,
    Protein Size: 667
    Molecular Weight
    72 kDa
    Gene ID
    64344
    NCBI Accession
    NM_152794, NP_690007
    UniProt
    Q9Y2N7
    Pathways
    Warburg Effect
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