TAF1C antibody (C-Term)
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- Target See all TAF1C Antibodies
- TAF1C (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))
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Binding Specificity
- C-Term
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Reactivity
- Mouse, Rat, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TAF1C antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RRHRGETSET QTQSKRPKRR TQLSSTFSSF TSYLDSPDAS SAPRSQDLST
- Predicted Reactivity
- Guinea Pig: 85%, Mouse: 100%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against Taf1c. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product TAF1C Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 836 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TAF1C (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))
- Alternative Name
- Taf1c (TAF1C Products)
- Synonyms
- TAF1C antibody, Tafi95 antibody, mTAFI95 antibody, MGC:39976 antibody, SL1 antibody, TAFI110 antibody, TAFI95 antibody, TATA-box binding protein associated factor, RNA polymerase I subunit C antibody, TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa antibody, TATA-box binding protein associated factor, RNA polymerase I, C antibody, TATA-box binding protein associated factor, RNA polymerase 1 subunit C antibody, TAF1C antibody, Taf1c antibody
- Background
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Taf1c is a component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Taf1c recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
Alias Symbols: Tafi95, mTAFI95
Protein Interaction Partner: Tbp, Taf1b, Taf1a,
Protein Size: 836 - Molecular Weight
- 92 kDa
- Gene ID
- 21341
- NCBI Accession
- NM_021441, NP_067416
- UniProt
- Q6PDZ2
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