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Cytokeratin 18 antibody (C-Term)

KRT18 Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778670
  • Target See all Cytokeratin 18 (KRT18) Antibodies
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    Binding Specificity
    • 25
    • 16
    • 15
    • 12
    • 11
    • 11
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 251
    • 150
    • 111
    • 44
    • 34
    • 27
    • 25
    • 21
    • 19
    • 17
    • 17
    • 14
    • 14
    • 14
    • 9
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig
    Host
    • 164
    • 122
    • 3
    • 1
    • 1
    Rabbit
    Clonality
    • 150
    • 141
    Polyclonal
    Conjugate
    • 143
    • 26
    • 22
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Cytokeratin 18 antibody is un-conjugated
    Application
    • 216
    • 99
    • 84
    • 78
    • 74
    • 60
    • 54
    • 40
    • 39
    • 27
    • 26
    • 19
    • 8
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    ALLNIKVKLE AEIATYRRLL EDGEDFNLGD ALDSSNSMQT IQKTTTRRIV
    Predicted Reactivity
    Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 77%, Rat: 100%, Zebrafish: 83%
    Characteristics
    This is a rabbit polyclonal antibody against KRT18. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human KRT18
    Top Product
    Discover our top product KRT18 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 430 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    Alternative Name
    KRT18 (KRT18 Products)
    Synonyms
    CK18 antibody, K18 antibody, Krt1-18 antibody, CYK18 antibody, DreK18 antibody, cb83 antibody, dapk1 antibody, sb:cb83 antibody, wu:fa13f02 antibody, wu:fb36b04 antibody, krt18 antibody, MGC64569 antibody, MGC75922 antibody, KRT18 antibody, CK-18-A antibody, K18-A antibody, NC-11 antibody, cyk18 antibody, k18 antibody, krt18-a antibody, krt18-b antibody, krt18a antibody, xkendob antibody, keratin 18 antibody, keratin 18, type I L homeolog antibody, keratin 18, type I antibody, keratin, type I cytoskeletal 18 antibody, K18, simple type I keratin antibody, Keratin, type I cytoskeletal 18 antibody, keratin 18, type I S homeolog antibody, Krt18 antibody, KRT18 antibody, krt18 antibody, krt18.L antibody, LOC700569 antibody, LOC100136778 antibody, k1c18 antibody, LOC100008885 antibody, krt18.S antibody
    Background
    KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
    Alias Symbols: K18, CYK18
    Protein Interaction Partner: KRT18, GOLGA2, UBC, HAUS1, CCDC146, MDM2, EED, HNRNPU, FLII, FKBP3, DDX1, C14orf166, RTCB, CNOT1, SEC16A, RPL14, RFC2, UPF2, BBS7, PAN2, BBS4, BBS2, BBS1, SMARCD1, ORC5, NOS2, KRT8, KPNA2, ITGA4, HRAS, GRN, FN1, EP300, ATF2, CDH1, CDC5L, YTHDC1, PIAS4, TX
    Protein Size: 430
    Molecular Weight
    47 kDa
    Gene ID
    3875
    NCBI Accession
    NM_000224, NP_000215
    UniProt
    P05783
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
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