FUS antibody (N-Term)

Catalog No. ABIN2778717

Product Details anti-FUS Antibody

Target: FUS (Fused in Sarcoma (FUS))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MASNDYTQQA TQSYGAYPTQ PGQGYSQQSS QPYGQQSYSG YSQSTDTSGY

Predicted Reactivity: Cow: 93%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against FUS. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FUS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 263 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FUS

Target: FUS (Fused in Sarcoma (FUS))

Alternative Name: FUS (FUS Products)

Synonyms: ALS6 antibody, ETM4 antibody, FUS1 antibody, HNRNPP2 antibody, POMP75 antibody, TLS antibody, D430004D17Rik antibody, D930039C12Rik antibody, Fus1 antibody, Tls antibody, FUS/TLS antibody, FUS RNA binding protein antibody, fused in sarcoma antibody, FUS antibody, Fus antibody

Target Type: Viral Protein

Background: FUS binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS may play a role in maintenance of genomic integrity.
Alias Symbols: FUS-CHOP, FUS1, TLS, ALS6, POMP75, HNRNPP2
Protein Interaction Partner: TBPL1, TRIP4, RPL14, HIST2H2BE, RAB7A, TUBA1A, DDX42, ATXN2L, CPSF6, NUDT21, YWHAQ, CKAP4, SF3A3, CCT8, PAICS, CCT2, CCT4, CCT7, SYNCRIP, TUBA1B, SF3A1, SF3B4, ABCF2, SAE1, SF1, YWHAZ, VCP, UBA1, UBC, TUFM, CCT3, HSP90B1, TP73, TKT, TCP1, TCEB1, STATH, ST
Protein Size: 526

Molecular Weight: 53 kDa

Gene ID: 2521

NCBI Accession: NM_001010850, NP_001010850

UniProt: P35637