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RED1 antibody (N-Term)

ADARB1 Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Cow, Dog, Horse, Guinea Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778757
  • Target See all RED1 (ADARB1) Antibodies
    RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))
    Binding Specificity
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 24
    • 19
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Zebrafish (Danio rerio), Cow, Dog, Horse, Guinea Pig, Rabbit
    Host
    • 20
    • 4
    • 3
    Rabbit
    Clonality
    • 25
    • 2
    Polyclonal
    Conjugate
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RED1 antibody is un-conjugated
    Application
    • 20
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    QLSNGGGGGP GRKRPLEEGS NGHSKYRLKK RRKTPGPVLP KNALMQLNEI
    Predicted Reactivity
    Cow: 83%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
    Characteristics
    This is a rabbit polyclonal antibody against ADARB1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ADARB1
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    Discover our top product ADARB1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 701 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

  • Target
    RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))
    Alternative Name
    ADARB1 (ADARB1 Products)
    Synonyms
    ADARB1 antibody, RED1 antibody, ADAR2 antibody, DRABA2 antibody, DRADA2 antibody, 1700057H01Rik antibody, AW124433 antibody, AW558573 antibody, Adar2 antibody, BB220382 antibody, D10Bwg0447e antibody, Red1 antibody, adar2 antibody, adarb1 antibody, red1 antibody, adenosine deaminase, RNA specific B1 antibody, adenosine deaminase, RNA-specific, B1 antibody, adenosine deaminase, RNA-specific, B1 L homeolog antibody, adenosine deaminase, RNA-specific, B1a antibody, ADARB1 antibody, adarb1 antibody, adarb1.L antibody, Adarb1 antibody, adarb1a antibody
    Background
    ADARB1 is an enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site.This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
    Alias Symbols: RED1, ADAR2, DRABA2, DRADA2
    Protein Interaction Partner: EBNA1BP2, IFRD2, CCDC124, NIFK, C7orf50, C1orf35, STRBP, BRIX1, SDAD1, ZFR, NOP16, MRTO4, RRS1, BMI1, APP, UBC, PPP2CB, WWP2, PIN1,
    Protein Size: 701
    Molecular Weight
    77 kDa
    Gene ID
    104
    NCBI Accession
    NM_001112, NP_001103
    UniProt
    Q4AE79
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