HNRNPK antibody (C-Term)
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- Target See all HNRNPK Antibodies
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Rabbit, Dog, Zebrafish (Danio rerio), Guinea Pig, Goat, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HNRNPK antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- YSYAGGRGSY GDLGGPIITT QVTIPKDLAG SIIGKGGQRI KQIRHESGAS
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against HNRPK. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human HNRPK
- Top Product
- Discover our top product HNRNPK Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 463 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
- Alternative Name
- HNRPK (HNRNPK Products)
- Background
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HNRPK belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Multiple alternatively spliced transcript variants have been described for this gene but only three variants have been fully described.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Multiple alternatively spliced transcript variants have been described for this gene but only three variants have been fully described.
Alias Symbols: CSBP, TUNP, HNRPK
Protein Interaction Partner: ZNF385C, ZFC3H1, RBMY1F, ZNF792, HNRNPLL, YTHDC1, PRR3, CCDC33, FBXL18, MARK4, PCDHB14, DALRD3, RASD1, RBMX, PRPF31, SORBS3, ABI2, HUWE1, MATR3, QKI, UBC, U2AF1, TYK2, TP53, SPG7, ZNRF2P1, C6orf226, RTP5, AQP5, GRB2, FUS, DOCK2, CIRBP, SNRPA, RBMY1A1, RBM
Protein Size: 463 - Molecular Weight
- 51 kDa
- Gene ID
- 3190
- NCBI Accession
- NM_031262, NP_112552
- UniProt
- P61978
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