RBMS1 antibody (Middle Region)

Catalog No. ABIN2778819

Product Details anti-RBMS1 Antibody

Target: RBMS1 (RNA Binding Motif, Single Stranded Interacting Protein 1 (RBMS1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Goat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBMS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GVSAPTEPLL CKFADGGQKK RQNPNKYIPN GRPWHREGEA GMTLTYDPTT

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RBMS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RBMS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 403 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RBMS1

Target: RBMS1 (RNA Binding Motif, Single Stranded Interacting Protein 1 (RBMS1))

Alternative Name: RBMS1 (RBMS1 Products)

Synonyms: C2orf12 antibody, HCC-4 antibody, MSSP antibody, MSSP-1 antibody, MSSP-2 antibody, MSSP-3 antibody, SCR2 antibody, YC1 antibody, 2600014B10Rik antibody, AI255215 antibody, RBMS1 antibody, fe16a10 antibody, wu:fe16a10 antibody, RNA binding motif single stranded interacting protein 1 antibody, RNA binding motif, single stranded interacting protein 1 antibody, RNA binding motif, single stranded interacting protein 1 S homeolog antibody, RNA binding motif, single stranded interacting protein 1a antibody, RBMS1 antibody, Rbms1 antibody, rbms1.S antibody, rbms1 antibody, rbms1a antibody

Background: RBMS1 is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis.This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Multiple transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. Several of these were isolated by virtue of their binding to either strand of an upstream element of c-myc (MSSPs), or by phenotypic complementation of cdc2 and cdc13 mutants of yeast (scr2), or as a potential human repressor of HIV-1 and ILR-2 alpha promoter transcription (YC1). A pseudogene for this locus is found on chromosome 12.
Alias Symbols: YC1, MSSP, SCR2, HCC-4, MSSP-1, MSSP-2, MSSP-3, C2orf12
Protein Interaction Partner: TFCP2, UBC, MRPL53, MRRF, SARNP, NABP2, SRPRB, SUGP1, SBDS, UBQLN1, TIMM44, HRSP12, PPIF, PQBP1, ZC3H11A, SNX3, STX7, UBE2I, SNRPC, SCP2, RRBP1, RPS19, RPL38, RFX5, PPIB, NDUFA7, DNM2, GRK5, POLA1,
Protein Size: 403

Molecular Weight: 44 kDa

Gene ID: 5937

NCBI Accession: NM_002897, NP_002888