EIF4G1 antibody (Middle Region)

Catalog No. ABIN2778919

Product Details anti-EIF4G1 Antibody

Target: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4G1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PAVPEVENQP PAGSNPGPES EGSGVPPRPE EADETWDSKE DKIHNAENIQ

Predicted Reactivity: Cow: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against EIF4G1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EIF4G1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1599 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EIF4G1

Target: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Alternative Name: EIF4G1 (EIF4G1 Products)

Synonyms: EIF4GI antibody, CG10811 antibody, Dmel\\CG10811 antibody, EIF4G antibody, Eif4G antibody, deIF4G antibody, eIF-4G antibody, eIF4g antibody, p200 antibody, EIF4G1 antibody, wu:fb50a05 antibody, wu:fc60b06 antibody, eif4g antibody, CUCUMOVIRUS MULTIPLICATION 2 antibody, CUM2 antibody, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G antibody, eukaryotic translation initiation factor 4G antibody, DDBDRAFT_0217646 antibody, DDBDRAFT_0217647 antibody, DDBDRAFT_0234257 antibody, DDB_0217646 antibody, DDB_0217647 antibody, DDB_0234257 antibody, NV18824 antibody, EIF-4G1 antibody, EIF4F antibody, P220 antibody, PARK18 antibody, p220 antibody, E030015G23Rik antibody, eIF4GI antibody, eukaryotic translation initiation factor 4 gamma 1 antibody, eukaryotic translation initiation factor 4G antibody, eukaryotic translation initiation factor 4 gamma, 1a antibody, eukaryotic translation initiation factor 4 gamma, 1 S homeolog antibody, eukaryotic initiation factor antibody, eukaryotic translation initiation factor 4 gamma antibody, eukaryotic translation initiation factor 4 gamma, 1 antibody, eukaryotic translation initiation factor 4, gamma 1 antibody, EIF4G1 antibody, eIF4G antibody, eif4g1a antibody, LOC704923 antibody, eif4g1.S antibody, EIF4G antibody, eIF4g antibody, Eif4g antibody, Eif4g1 antibody

Background: EIF4G1 is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure, and recruitment of mRNA to the ribosome.The protein encoded by this gene is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure, and recruitment of mRNA to the ribosome. Alternative splicing results in five transcript variants encoding four distinct isoforms.
Alias Symbols: DKFZp686A1451, EIF4F, EIF4G, p220, P220, EIF4GI, PARK18, EIF-4G1
Protein Interaction Partner: POLDIP3, EIF4E, UBC, NCBP1, SUMO1, SUMO2, MDM2, LGR4, AIMP1, IQGAP1, EEF1E1, AIMP2, QARS, PTBP1, PSMB8, TARDBP, UBD, BRCA1, ITGA4, GK, FN1, HTRA2, ZFYVE9, VCAM1, HNRNPD, ESR1, EIF4G3, FTL, EIF4G2, RAB31, SF3A3, EIF4B, EIF4A1, TRAF2, CUL3, ISG15, YWHAZ, SI
Protein Size: 1599

Molecular Weight: 175 kDa

Gene ID: 1981

NCBI Accession: NM_182917, NP_886553

UniProt: Q04637