IGF2BP2 antibody (Middle Region)

Catalog No. ABIN2778996

Product Details anti-IGF2BP2 Antibody

Target: IGF2BP2 (Insulin-Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2BP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QANLIPGLNL SALGIFSTGL SVLSPPAGPR GAPPAAPYHP FTTHSGYFSS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 100%, Yeast: 77%

Characteristics: This is a rabbit polyclonal antibody against IGF2BP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IGF2BP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 599 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IGF2BP2

Target: IGF2BP2 (Insulin-Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2))

Alternative Name: IGF2BP2 (IGF2BP2 Products)

Synonyms: IMP-2 antibody, IMP2 antibody, VICKZ2 antibody, p62 antibody, C330012H03Rik antibody, Imp2 antibody, Neilsen antibody, RGD1305614 antibody, insulin like growth factor 2 mRNA binding protein 2 antibody, insulin-like growth factor 2 mRNA binding protein 2 antibody, IGF2BP2 antibody, Igf2bp2 antibody

Background: IGF2BP2 binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs.
Alias Symbols: IMP-2, IMP2, VICKZ2, p62
Protein Interaction Partner: UBC, STAU1, WWOX, SAV1, TARDBP, EIF2AK2, CBX8, CBX6, ITGA4, FN1, PA2G4, PPAP2A, RAB5A, CAND1, CUL3, HNRNPD, SIRT7, ARRB1, ELAVL1, Mapk13, MYC, ICT1, MEPCE, HNRNPA1, CDK9, PUF60,
Protein Size: 599

Molecular Weight: 66 kDa

Gene ID: 10644

NCBI Accession: NM_006548, NP_006539

UniProt: Q9Y6M1