ADAT1 antibody (C-Term)

Catalog No. ABIN2779030

Product Details anti-ADAT1 Antibody

Target: ADAT1 (Adenosine Deaminase, tRNA-Specific 1 (ADAT1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LFRSFQKLLS RIARDKWPHS LRVQKLDTYQ EYKEAASSYQ EAWSTLRKQV

Predicted Reactivity: Dog: 79%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ADAT1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADAT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 502 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADAT1

Target: ADAT1 (Adenosine Deaminase, tRNA-Specific 1 (ADAT1))

Alternative Name: ADAT1 (ADAT1 Products)

Synonyms: ADAT1 antibody, zgc:162299 antibody, HADAT1 antibody, MMADAT1 antibody, mADAT1 antibody, adenosine deaminase, tRNA specific 1 antibody, adenosine deaminase, tRNA-specific 1 antibody, ADAT1 antibody, adat1 antibody, Adat1 antibody

Background: ADAT1 is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, the family participates in the pre-mRNA editing of nuclear transcripts. ADAT1, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA.This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA.
Alias Symbols: HADAT1
Protein Interaction Partner: UBC, ELAVL1,
Protein Size: 502

Molecular Weight: 55 kDa

Gene ID: 23536

NCBI Accession: NM_012091, NP_036223

UniProt: Q9BUB4