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OAS2 antibody (Middle Region)

OAS2 Reactivity: Human, Pig, Rabbit, Dog, Cow WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2779107
  • Target See all OAS2 Antibodies
    OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
    Binding Specificity
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 30
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Pig, Rabbit, Dog, Cow
    Host
    • 23
    • 6
    • 2
    Rabbit
    Clonality
    • 25
    • 6
    Polyclonal
    Conjugate
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OAS2 antibody is un-conjugated
    Application
    • 18
    • 13
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    AKGTALKTGS DADLVVFHNS LKSYTSQKNE RHKIVKEIHE QLKAFWREKE
    Predicted Reactivity
    Cow: 92%, Dog: 92%, Human: 100%, Pig: 100%, Rabbit: 85%
    Characteristics
    This is a rabbit polyclonal antibody against OAS2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human OAS2
    Top Product
    Discover our top product OAS2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 719 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
    Alternative Name
    OAS2 (OAS2 Products)
    Synonyms
    Oasl11 antibody, 2'-5'-oligoadenylate synthetase 2 antibody, 2'-5' oligoadenylate synthetase 2 antibody, 2'-5'-oligoadenylate synthetase 2, 69/71kDa antibody, OAS2 antibody, Oas2 antibody
    Background
    OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
    Alias Symbols: MGC78578
    Protein Interaction Partner: UBC, CLK3, APP,
    Protein Size: 719
    Molecular Weight
    82 kDa
    Gene ID
    4939
    NCBI Accession
    NM_016817, NP_058197
    UniProt
    P29728
    Pathways
    Hepatitis C
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