HSPA9 antibody (C-Term)

Catalog No. ABIN2779292

Product Details anti-HSPA9 Antibody

Target: HSPA9 (Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Dog, Rabbit, Guinea Pig, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPA9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequence: GENIRQAASS LQQASLKLFE MAYKKMASER EGSGSSGTGE QKEDQKEEKQ

Predicted Reactivity: Cow: 85%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HSPA9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HSPA9

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 679 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HSPA9 antibody (ABIN2779292)

Shi, Liu, Zhang, Qin, Zhang, Li, Chen: "[Cloning and sequence analysis of the Meq gene of 4 Marek's disease virus isolates from China]." in: Bing du xue bao = Chinese journal of virology / [bian ji, Bing du xue bao bian ji wei yuan hui], Vol. 24, Issue 2, pp. 117-25, (2008) (PubMed).

Target Details for HSPA9

Target: HSPA9 (Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9))

Alternative Name: HSPA9 (HSPA9 Products)

Synonyms: APG-2 antibody, HS24/P52 antibody, HSPH2 antibody, RY antibody, hsp70 antibody, hsp70RY antibody, CSA antibody, GRP-75 antibody, GRP75 antibody, HSPA9B antibody, MOT antibody, MOT2 antibody, MTHSP75 antibody, PBP74 antibody, Hspa9a antibody, csa antibody, grp-75 antibody, grp75 antibody, hspa9 antibody, hspa9b antibody, mortalin antibody, mot antibody, mot2 antibody, pbp74 antibody, mot-2 antibody, mthsp75 antibody, 74kDa antibody, Csa antibody, Grp75 antibody, Hsc74 antibody, Hsp74 antibody, Hsp74a antibody, Mortalin antibody, Mot-2 antibody, Mot2 antibody, Mthsp70 antibody, Pbp74 antibody, cb740 antibody, crs antibody, wu:fc14d08 antibody, wu:fc27c10 antibody, wu:fc38a06 antibody, heat shock protein family A (Hsp70) member 4 antibody, heat shock protein family A (Hsp70) member 9 antibody, heat shock protein family A member 9 antibody, heat shock protein family A (Hsp70) member 9 S homeolog antibody, stress-70 protein, mitochondrial antibody, heat shock protein 9 antibody, heat shock protein Hsp9 antibody, HSPA4 antibody, HSPA9 antibody, Hspa9 antibody, hspa9.S antibody, hspa9 antibody, LOC577721 antibody, hsp9 antibody

Background: HSPA9 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA9 is a heat-shock cognate protein. This protein plays a role in the control of cell proliferation. It may also act as a chaperone.CSHL1 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein.The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein plays a role in the control of cell proliferation. It may also act as a chaperone. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants have been observed, but most of them are not thought to be protein-coding.
Alias Symbols: CSA, GRP75, HSPA9B, MGC4500, MOT, MOT2, MTHSP75, PBP74, mot-2, GRP-75
Protein Interaction Partner: GPX7, FUS, CDKN2A, UBC, TP53, YKT6, CDKN1A, CDC20, CEP250, TUBGCP2, CEP57, AURKB, TUBG1, AURKA, SUMO2, SUMO3, NEDD1, SPRTN, CEP76, HAUS2, TUBGCP4, STAU1, GRSF1, NEDD8, MDM2, EED, RAP1GDS1, PFAS, GINS3, ATG3, OSGEP, BZW2, ABHD14A, TNFAIP8, FERMT2, AIP, CNB
Protein Size: 679

Molecular Weight: 75 kDa

Gene ID: 3313

NCBI Accession: NM_004134, NP_004125

UniProt: P38646