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Amphiregulin antibody (Middle Region)

AREG Reactivity: Human, Cow, Sheep, Dog, Horse, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2779308
  • Target See all Amphiregulin (AREG) Antibodies
    Amphiregulin (AREG)
    Binding Specificity
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Cow, Sheep, Dog, Horse, Pig
    Host
    • 27
    • 9
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 31
    • 8
    Polyclonal
    Conjugate
    • 27
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Amphiregulin antibody is un-conjugated
    Application
    • 26
    • 14
    • 10
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PQIPGYIVDD SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR
    Predicted Reactivity
    Cow: 91%, Dog: 91%, Horse: 91%, Human: 100%, Pig: 91%, Sheep: 91%
    Characteristics
    This is a rabbit polyclonal antibody against AREG. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human AREG
    Top Product
    Discover our top product AREG Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 252 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Amphiregulin (AREG)
    Alternative Name
    AREG (AREG Products)
    Synonyms
    AR antibody, CRDGF antibody, SDGF antibody, Sdgf antibody, AREG antibody, AREGB antibody, AREG/SDGF antibody, amphiregulin antibody, AREG antibody, Areg antibody
    Background
    The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.
    Alias Symbols: AR, AREGB, CRDGF, MGC13647, SDGF
    Protein Interaction Partner: KRTAP10-3, WDR92, UBC, APP, UBQLN4, WT1, EGFR, CCND3, MMP9,
    Protein Size: 252
    Molecular Weight
    28 kDa
    Gene ID
    374
    NCBI Accession
    NM_001657, NP_001648
    UniProt
    P15514
    Pathways
    RTK Signaling, EGFR Signaling Pathway
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