GSC antibody (N-Term)

Catalog No. ABIN2779490

Product Details anti-GSC Antibody

Target: GSC (Goosecoid Homeobox (GSC))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: FPALHGDSLY GASGGASSDY GAFYPRPVAP GGAGLPAAVS GSRLGYNNYF

Predicted Reactivity: Cow: 86%, Dog: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against GSC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 257 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GSC antibody (ABIN2779490)

Behl, Hsieh, Shafer, Mundy, Rice, Boyd, Freedman, Hunter, Jarema, Padilla, Tice: "Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity." in: Neurotoxicology and teratology, Vol. 52, Issue Pt B, pp. 181-93, (2015) (PubMed).

Target Details for GSC

Target: GSC (Goosecoid Homeobox (GSC))

Alternative Name: GSC (GSC Products)

Synonyms: ZGSC antibody, MGC101595 antibody, zgc:101595 antibody, ik:tdsubc_2g4 antibody, xx:tdsubc_2g4 antibody, ik:tdsubc_1c10 antibody, ik:tdsubc_2h11 antibody, xx:tdsubc_1c10 antibody, xx:tdsubc_2h11 antibody, 60Mun1 antibody, 60Mun2 antibody, CG2851 antibody, D-Gsc antibody, D-gsc antibody, Dmel\\CG2851 antibody, M72 antibody, PPH25 antibody, Pph25 antibody, gsc antibody, l(2)05341 antibody, Xgsc antibody, goosecoid antibody, GSC antibody, gsc-a antibody, gsc-b antibody, goosecoid antibody, Goosecoid antibody, goosecoid homeobox S homeolog antibody, goosecoid homeobox antibody, goosecoid homeobox L homeolog antibody, gsc antibody, Gsc antibody, gsc.S antibody, GSC antibody, gsc.L antibody

Background: GSC regulates chordin (CHRD). GSC may play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis.This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis.
Alias Symbols: -
Protein Interaction Partner: SMAD3, SMAD1, SMAD2, FOXA2,
Protein Size: 257

Molecular Weight: 28 kDa

Gene ID: 145258

NCBI Accession: NM_173849, NP_776248

UniProt: P56915