NK2 Homeobox 3 antibody (Middle Region)

Catalog No. ABIN2779498

Product Details anti-NK2 Homeobox 3 Antibody

Target: NK2 Homeobox 3 (NKX2-3)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NK2 Homeobox 3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AHAPPPPPRR VAVPVLVRDG KPCVTPSAQA YGAPYSVGAS AYSYNSFPAY

Predicted Reactivity: Cow: 87%, Dog: 93%, Guinea Pig: 87%, Human: 100%, Mouse: 80%, Rat: 87%

Characteristics: This is a rabbit polyclonal antibody against NKX2-3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NKX2-3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 364 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NK2 Homeobox 3

Target: NK2 Homeobox 3 (NKX2-3)

Alternative Name: NKX2-3 (NKX2-3 Products)

Synonyms: CSX3 antibody, NK2.3 antibody, NKX2.3 antibody, NKX2C antibody, NKX4-3 antibody, Nkx-2.3 antibody, Nkx2.3 antibody, tinman antibody, CNKX-2.3 antibody, NK2 homeobox 3 antibody, NK2 transcription factor related, locus 3 antibody, NKX2-3 antibody, Nkx2-3 antibody

Background: NKX2C is a member of the NKX family of homeodomain-containing transcription factors, which are implicated in many aspects of cell type specification and maintenance of differentiated tissue functions.NKX2C is a member of the NKX family of homeodomain-containing transcription factors, which are implicated in many aspects of cell type specification and maintenance of differentiated tissue functions. See Harvey (1996) [PubMed 8812123] for a review of the structure, regulation, function, and evolution of NK2 homeobox genes with an emphasis on their roles in heart development.[supplied by OMIM]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by orthologous data and transcript alignments.
Alias Symbols: CSX3, NKX2.3, NKX2C, NKX4-3, NK2.3
Protein Interaction Partner: ZNF212, GTF2A1L, SRF,
Protein Size: 364

Molecular Weight: 38 kDa

Gene ID: 159296

NCBI Accession: NM_145285, NP_660328

UniProt: Q8TAU0